Acute febrile mucocutaneous syndrome is an acute systemic vacuities involving medium sized vessels, affecting mainly children under 5 years of age (1). Affect mainly to children 6 months to 4 years of age. This is common in Japan. Young infant more tend to be more severally affected than older children.Cause is unknown, but the many clinical and immunologicalsimilarities with the staphylococcal and streptococcal toxic shock syndromes have led to the suggestion that it is also caused by bacterial toxin acting as a super antigen(2).